About Prozac: To overcome the shortcomings of the tricyclic antidepressant drugs (TCAs), selective serotonin re uptake inhibitors (SSRIs) were developed in the 1980s and Prozac (Fluoxetine) was one the first of these. Since then, Prozac has found a wide variety of uses such as major depression, bipolar disorder, bulimia nervosa, and obsessive – compulsive disorder. It was found to be better than TCAs since it had a better safety profile, lower incidence of anticholinergic, cardiovascular and neurological side effects; and found to be effective in most patients with a good response.
How Prozac Works: It was found that serotonin when present in higher quantities as a neurotransmitter in the brain, lightens the mood of a person. However, re – uptake of serotonin back into the ends of synapses that release it is very rapid. Hence the effect of serotonin on the mood is short lived. Prozac and other SSRIs were found to decrease this uptake of serotonin back into the synaptic terminals and prolong its neurotransmitter effect. This is the basis of the antidepressive action of Prozac. The side effect profile of Prozac is better than the TCAs as the TCAs inhibit the re – uptake of noradrenaline and dopamine at the nerve synaptic cleft and have a strong anti – cholinergic action as well.
How To Take Prozac: Prozac must be taken only on the advice of a registered medical practitioner and it is strictly a prescription drug. The action of Buy Prozac may take about 2 – 4 weeks to appear and it necessary for the patient to be aware of this as regular visits to the psychiatrist should be maintained in the interim period. Prozac 20mg is used in the therapy of major depressive disorder, bipolar disorder involving alternating episodes of mania or hypomania and depression, in bulimia nervosa and obsessive compulsive disorder. Of these its main usage is in acute and maintenance treatment of major depression.
Prozac is available as an oral capsule in the strengths of 10 mg, 20 mg and 40 mg. For the treatment of major depression, usually a starting dose of 20 mg/ day is recommended. The dosage of Prozac No Prescription can be increased if the clinical response is not adequate, but not more than 80 mg/ day. The drawback of Buy Prozac No Prescription is that the action takes 2 – 4 weeks to appear and clinical response cannot be judged till this time. Once patients have responded to the medication, they are kept on a daily maintenance does, usually 20 mg/ day.
In Obsessive Compulsive Disorder (OCD), Buy Prozac is started at an initial dose of 20 mg daily, taken in the morning. Generally a dose in the range of 20 mg – 60 mg is recommended. The therapeutic benefit may take up to 5 weeks after starting treatment. Maintenance dose of Buy Prozac Without Prescription is at 20 mg/ day.
For usage in therapy of bulimia nervosa and panic disorder, similar dosage regimens are to be followed. However, Prozac should not be taken without advice of a psychiatrist.
It is imperative that the physician maintain a good follow – up of patients who are started on Prozac, since the effect of the drug has been seen to wane in a few patients after 10 – 12 weeks, and this could lead to dangerous behavioural changes (e.g. re-emergence of suicidal tendencies).
Precautions And Interactions: Prozac Without Prescription and other antidepressive medications have been reported to increase the risk of suicidal ideation in younger patients. It has been contested that the increase in suicidal intent or ideation does not translate in to actual suicide. However, caution is to be exercised in this respect.
The concomitant use of Prozac 20mg with other serotonergic agents such as sumatriptan, tramadol, etc. can cause serotonin syndrome, a dangerous side effect.
Side Effects Of Prozac: Common side effects seen with Prozac No Prescription include nausea, insomnia or drowsiness, anorexia, anxiety, headache, agitation and irritability. Prozac Without Prescription and other SSRIs can lead to sexual problems such as decreased libido, impotence, and anorgasmia.
Other rare side effects of Buy Prozac 20mg include hyponatremia, serotonin syndrome or neurolept malignant syndrome, abnormal bleeding, risk of seizures and allergic reactions.